DEA form 222 must be used when purchasing:

The requirement to use DEA Form 222 specifically pertains to the procurement of controlled substances categorized as Schedule I (C1) and Schedule II (C2) drugs. This form serves as a critical part of the regulatory framework established by the Drug Enforcement Administration (DEA) to monitor and record the distribution of these highly regulated substances.

Controlled substances are classified into schedules based on their potential for abuse and dependency. Schedule I drugs are deemed to have no accepted medical use and a high potential for abuse, while Schedule II drugs have accepted medical uses but still pose a significant risk for abuse and dependency. The use of DEA Form 222 is mandated for transactions involving these categories to ensure strict control and accountability, thereby reducing the risk of misuse or illegal distribution.

In contrast, regular prescription drugs that are not classified as Schedule I or II, as well as non-controlled substances, do not necessitate the use of Form 222 for purchasing. This form is exclusively meant for Schedule I and II substances. Understanding the specific application of this form is crucial for compliance with federal laws governing the sale and distribution of controlled substances, highlighting the importance of proper documentation in pharmacy operations.